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Uganda Virus Research Institute


Personal Protective Equipment (PPE) for Vaccine Administration

The sitting arrangement of the vaccinee and the vaccinator. These two should not directly face each other. Ideal should be 90 degrees arrangement.


Persons administering vaccinations should follow appropriate precautions to minimize risk for disease exposure and spread. Hands should be cleansed with an alcohol-based waterless antiseptic hand rub or washed with soap and water before preparing vaccines for administration and between each patient contact.

Gloves are not recommended for most vaccination administration and are not required for the COVID-19 vaccine unless the person administering the vaccine is likely to get into contact with potentially infectious body fluids or has open lesions on their hands. The sitting arrangement of the vaccinee and the vaccinator should not directly face each other. Ideal should be 90 degrees arrangement.

If used improperly, gloves can increase the likelihood of spreading germs. If gloves are worn during vaccine administration:

  • They should be changed between patients along with performing proper hand hygiene.
  • Vinyl gloves are appropriate.
  • If nitrile gloves are a limited resource, prioritize/consider appropriate uses for nitrile gloves.
  • Gloves are single use and cannot be washed. If worn, gloves should be changed between patients.
  • Improper aseptic technique or hand hygiene measures can increase the risk of infections in both the patient and the individual performing the vaccination.

Other PPE Requirements

  • Vaccine providers should follow standard precautions and transmission-based precautions outlined by the Centers for Disease Control and Prevention.
  • A face mask and eye protection are required based on current community transmission. Healthcare personnel working facilities located in areas with moderate to substantial community transmission should wear a face mask and eye protection with every patient encounter. These do not need to be changed between patients unless they are soiled. An N95 or equivalent higher-level respirator is not generally required for vaccine administration unless indicated by transmission-based precautions.


Hand Hygiene

Implement infection control measures before patient arrival, upon arrival, throughout the visit, and until fully cleaned and disinfected. Staff must perform hand hygiene between each vaccination administration. Urge the importance of hand hygiene for patients and visitors that includes the use of soap and water, or alcohol-based hand sanitizer.